This looks as though it is a hosted ad server application that uses ASP to manage the delivery of code. The system seems to be similar to google's adsense in as much as you obtian several lines of code from them to insert onto your pages wherever you want the banners to appear.
So - yes this will work with vB
systems. You simply need to sign up with them, get your code and insert this code into whichever template you wish the codee to appear in.